Most Important MCQs of Human Diseases -updated 2025 – GS
1. Parkinson is a disease of _____.
Correct Answer: B. Brain
Explanation: Parkinson’s disease is a neurodegenerative disorder affecting the brain and movement control.
2. “Cataract” is a disease of:
Correct Answer: C. Eyes
Explanation: Cataract affects the eyes by causing clouding of the lens and reduced vision.
3. “Jaundice” is the disease of:
Correct Answer: A. Liver
Explanation: Jaundice primarily affects the liver and causes yellowing of the skin and eyes.
4. “Pellagra” is a disease of:
Correct Answer: A. Skin
Explanation: Pellagra is a skin-related disease caused by deficiency of Vitamin B3 (niacin).
5. Myopia is a disease of ______.
Correct Answer: B. Eyes
Explanation: Myopia (nearsightedness) is a vision condition affecting the eyes.
6. “Osteomyelitis” is a disease of:
Correct Answer: A. Bones
Explanation: Osteomyelitis is a bacterial infection of the bones.
7. Malaria is a disease of _____.
Correct Answer: A. Blood (RBC), Liver and Spleen
Explanation: Malaria affects red blood cells, liver, and spleen and is caused by Plasmodium parasites.
8. “Diphtheria” is a disease of:
Correct Answer: B. Throat
Explanation: Diphtheria is an infectious disease of the throat caused by bacteria.
9. “Arthritis” is a human disease that affects _____.
Correct Answer: A. Joints
Explanation: Arthritis is an inflammation of the joints causing pain and stiffness.
10. “Pneumonia” is a human disease that affects _______.
Correct Answer: A. Lungs
Explanation: Pneumonia is an infection that primarily affects the lungs.
11. “Pyorrhea” is a human disease that affects _____.
Correct Answer: A. Gums
Explanation: Pyorrhea is a gum disease (periodontitis) that leads to swelling, bleeding, and loosening of teeth.
12. “Otitis” is a disease of:
Correct Answer: A. Ears
Explanation: Otitis is an inflammation of the ear, commonly known as an ear infection.
13. “Colitis” is a human disease that affects _____.
Correct Answer: A. Intestine
Explanation: Colitis is an inflammation of the colon (large intestine), often causing abdominal pain and diarrhea.
14. “Glossitis” is a human disease that affects _____.
Correct Answer: A. Tongue
Explanation: Glossitis is inflammation of the tongue, leading to swelling, pain, and changes in texture.
15. “Insomnia” is a condition of _____.
Correct Answer: A. Inability to sleep
Explanation: Insomnia is a sleep disorder characterized by difficulty falling or staying asleep.
16. Leukemia is a disease in which:
Correct Answer: C. Too many white blood cells are produced
Explanation: Leukemia is a type of blood cancer where abnormal white blood cells are produced excessively in the bone marrow.
17. Haemophilia is caused by:
Correct Answer: B. Defective genes
Explanation: Haemophilia is a genetic disorder where blood does not clot properly due to defective clotting factor genes.
18. Psoriasis is:
Correct Answer: B. A skin disease
Explanation: Psoriasis is a chronic skin disease that speeds up the life cycle of skin cells, causing scaly patches.
19. LSD is _________.
Correct Answer: B. A hallucinogenic drug that affects the human mind
Explanation: LSD (Lysergic acid diethylamide) is a hallucinogenic drug that alters perception, mood, and cognitive processes.
20. Diabetes Mellitus is a disease of:
Correct Answer: A. Blood sugar regulation
Explanation: Diabetes Mellitus is a chronic condition where the body cannot properly regulate blood sugar due to insulin problems.
21. Hypertension is a condition of ______.
Correct Answer: B. Increased blood pressure
Explanation: Hypertension refers to high blood pressure, which can lead to heart disease, stroke, and other complications if uncontrolled.
22. Tuberculosis primarily affects the:
Correct Answer: B. Lungs
Explanation: Tuberculosis (TB) is caused by Mycobacterium tuberculosis and primarily affects the lungs, though it can spread to other organs.
23. HIV/AIDS is, a human disease, caused by a virus that affects _____.
Correct Answer: A. The immune system
Explanation: HIV (Human Immunodeficiency Virus) attacks the immune system, specifically CD4 cells, weakening the body’s defense against infections.
24. Asthma is a disease of the:
Correct Answer: A. Lungs
Explanation: Asthma is a chronic condition that affects the airways in the lungs, making breathing difficult due to inflammation and narrowing.
25. Alzheimer’s Disease primarily affects the ______.
Correct Answer: C. Brain
Explanation: Alzheimer’s disease is a progressive brain disorder that destroys memory and cognitive functions, mainly affecting older adults.
MCQs related to human diseases frequently appear in competitive exams as a part of general Science section. These questions are designed to assess a candidate’s understanding of basic human physiology and their awareness of the human body. It’s not just about knowing the environment or current affairs — candidates are also tested on how well they understand themselves: what organs perform which functions, what diseases can affect those functions, and how the body responds to various conditions.
This knowledge reflects a candidate’s critical thinking and awareness of both internal and external factors affecting human life. Recognizing this importance, we have prepared a comprehensive list of Human Diseases MCQs that will prove helpful in your exam preparation. The list is provided below: